This study was performed to investigate the effects of dietary protein content on recovery of laparotomized rats in terms of urinary epinephrine and norepinephrine, plasma epinephrine nd norepinephrine. Fortyeight male Sprague Dawley rats
average-weighing 160g were divided into two groups : LPD(10% low protein diet) group. HPD(25% high protein diet) group After 3 days of adaptation period, rats were given experimental diet for 14 days. Experimental period consists of 7-days
pre-trauma
and 7-days post-trauma period. Rats were laparotomized by 4cm abdominal under sodium pentobarbital anesthesia During 7-days before and norepinephrine.
@ES The results are as follows :
@EN After laparotomy, urinary epinephrine level was not increased in two diet groups. Urinary epinephrine concentration of rats in LPD group was considerably increased in post-trauma day 3 and thereafter gradually reduced By post-trauma day 4,
however,
urinary epinephrine concentration of rats in HPD group was recovered to pre-trauma level.
2) Urinary norepinephrine concentration of rats in LPD group was significantly increased after trauma(p<0.01) and the difference between LPD and HPD in post-trauma asverage norepinephrine concentration was not significant.
3) Post-traum average plasma epinephrine concentration was higher, but not significant.than that of pre-trauma average in both groups [LPD(19.88ng/ml vs 20.93mg/ml). HPD(17.20ng/ml vs 19.37ng/ml)]
4) Plasma norepinephrine concentration of rats in LPD group was significantly increased. in post-trauma period(p<0.01) In HPD group however, post-trauma average plasma norepinephrine concentration was significantly lower than pre-trauma average.
Thus. The results suggest that norepinehrine concentration was affected by trauma and rats in HPD group excreted less amount of norepinephrine than rats in LPD group.
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